Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rs10204525 Polymorphism of the Programmed Death (PD-1) Gene Is Associated with Increased Risk in a Saudi Arabian Population with Colorectal Cancer.

Medicina (Kaunas, Lithuania) - 13 Oct 2022

Al-Harbi Nouf, Vaali-Mohammed Mansoor-Ali, Al-Omar Suliman, Zubaidi Ahmed, Al-Obeed Omar, Abdulla Maha-Hamadien, Mansour Lamjed

Abstract excerpt

Checkpoint programmed death-1 (PD-1) has been identified as an immunosuppressive molecule implicated in the immune evasion of transformed cells. It is highly expressed in tumor cells in order to evade host immunosurveillance. In this study, we aimed to assess the association between single nucleotide polymorphisms (SNP) of PD-1 and the risk of colorectal cancer (CRC) in the Saudi population. For this case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Programmed Cell Death 1 Receptor

Share to Saudi Arabia

Source

Open in PubMed Open full text

Identifiers

PMID: 36295599
DOI: 10.3390/medicina58101439
PMCID: PMC9607617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rs10204525 Polymorphism of the Programmed Death (PD-1) Gene Is Associated with Increased Risk in a Saudi Arabian Population with Colorectal Cancer.PMID 36295599Read ↗

Association of PD-1 and PDL-1 gene polymorphisms with colorectal cancer risk and prognosis.Semantic proximity Read ↗

[Association of programmed cell death 1 (PDCD1) gene polymorphisms with colorectal cancer among Han Chinese population].Semantic proximity Read ↗

Evidence of Association between CTLA-4 Gene Polymorphisms and Colorectal Cancers in Saudi Patients.Semantic proximity Read ↗

Lack of Association Between PDCD-1 Polymorphisms and Colorectal Cancer Risk: A Case-Control Study.Semantic proximity Read ↗

Programmed death-1 gene polymorphism (PD-1.5 C/T) is associated with colon cancer.Semantic proximity Read ↗

Single nucleotide variants associated with colorectal cancer among Saudi patients: A systematic review.Semantic proximity Read ↗

Distribution of PD-1.5 Gene Variant (rs2227981): A Possible Approach for Risk Assessment in Bladder Cancer.Semantic proximity Read ↗

Programmed Cell Death-1 Polymorphisms Decrease the Cancer Risk: A Meta-Analysis Involving Twelve Case-Control Studies.Semantic proximity Read ↗

Associations of PD-1 and PD-L1 gene polymorphisms with cancer risk: a meta-analysis based on 50 studies.Semantic proximity Read ↗

Association between polymorphisms in PRNCR1 and risk of colorectal cancer in the Saudi populationSemantic proximity Read ↗

Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer.Semantic proximity Read ↗

Novel genetic loci and functional properties of immune-related genes for colorectal cancer survival in KoreaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.