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Article

Programmed death-1 gene polymorphism (PD-1.5 C/T) is associated with colon cancer.

Gene - 25 Oct 2012

Mojtahedi Zahra, Mohmedi Mona, Rahimifar Shahrzad, Erfani Nasrollah, Hosseini Seyed Vahid, Ghaderi Abbas

Abstract excerpt

Programmed death-1 (PD-1), expressed by activated T cells, is a negative regulator of T lymphocytes. The associations of the immune response-related genes with cancer have been demonstrated. In this study, the PD-1.5 C/T (+7785) polymorphism was investigated in 200 colorectal cancer patients and 200 healthy individuals as controls by nested polymerase chain reaction-restriction fragment length polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22892379
DOI: 10.1016/j.gene.2012.07.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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