Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample.

Brain, behavior, and immunity - 1 May 2018

Parks Samuel, Avramopoulos Dimitrios, Mulle Jennifer, McGrath John, Wang Ruihua, Goes Fernando S, Conneely Karen, Ruczinski Ingo, Yolken Robert, Pulver Ann E, Pearce Brad D

Abstract excerpt

BACKGROUND: The infections Toxoplasma gondii (T. gondii), cytomegalovirus, and Herpes Simplex Virus Type 1 (HSV1) are common persistent infections that have been associated with schizophrenia and bipolar disorder. The major histocompatibility complex (MHC, termed HLA in humans) region has been implicated in these infections and these mental illnesses. The interplay of MHC genetics, mental illness, and infection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Cytomegalovirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpesvirus 1, Human

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Infections

Share to Schizophrenia

Share to Toxoplasma

Source

Open in PubMed Open full text

Identifiers

PMID: 29574260
DOI: 10.1016/j.bbi.2018.03.001
PMCID: PMC12919707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample.PMID 29574260Read ↗

A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders.Semantic proximity Read ↗

Understanding the genetic contribution of the human leukocyte antigen system to common major psychiatric disorders in a world pandemic context.Semantic proximity Read ↗

Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure.Semantic proximity Read ↗

An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample.Semantic proximity Read ↗

Infection and inflammation in schizophrenia and bipolar disorder: a genome wide study for interactions with genetic variation.Semantic proximity Read ↗

Immunogenetic Variants in Major Mental and Neurodevelopmental Disorders.Semantic proximity Read ↗

Major histocompatibility complex genomics and human disease.Semantic proximity Read ↗

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population.Semantic proximity Read ↗

Dissecting the genetic relationship between severe mental disorders and autoimmune diseases.Semantic proximity Read ↗

Dissecting the Genetic Relationship Between Severe Mental Disorders and Autoimmune DiseasesSemantic proximity Read ↗

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - Findings from a Danish population-based study.Semantic proximity Read ↗

A transcriptome-wide Mendelian randomization study in isolated human immune cells highlights risk genes involved in viral infections and potential drug repurposing opportunities for schizophreniaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.