Article
Infection and inflammation in schizophrenia and bipolar disorder: a genome wide study for interactions with genetic variation.
PloS one - 1 Jan 2015
Avramopoulos Dimitrios, Pearce Brad D, McGrath John, Wolyniec Paula, Wang Ruihua, Eckart Nicole, Hatzimanolis Alexandros, Goes Fernando S, Nestadt Gerald, Mulle Jennifer, Coneely Karen, Hopkins Myfanwy, Ruczinski Ingo, Yolken Robert, Pulver Ann E
Abstract excerpt
Inflammation and maternal or fetal infections have been suggested as risk factors for schizophrenia (SZ) and bipolar disorder (BP). It is likely that such environmental effects are contingent on genetic background. Here, in a genome-wide approach, we test the hypothesis that such exposures increase the risk for SZ and BP and that the increase is dependent on genetic variants. We use genome-wide genotype data,...
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