Article
Understanding the genetic contribution of the human leukocyte antigen system to common major psychiatric disorders in a world pandemic context.
Brain, behavior, and immunity - 1 Jan 2021
Tamouza Ryad, Krishnamoorthy Rajagopal, Leboyer Marion
Abstract excerpt
The human leukocyte antigen (HLA) is a complex genetic system that encodes proteins which predominantly regulate immune/inflammatory processes. It can be involved in a variety of immuno-inflammatory disorders ranging from infections to autoimmunity and cancers. The HLA system is also suggested to be involved in neurodevelopment and neuroplasticity, especially through microglia regulation and synaptic pruning....
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