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Article

Immunogenetic Variants in Major Mental and Neurodevelopmental Disorders.

Biological psychiatry - 1 Jun 2026

Le Clerc Sigrid, Bernard Jeremy, Choi Jaehyoung, Andreazza Ana C, Zagury Jean-François, Leboyer Marion

Abstract excerpt

Major mental disorders (MMDs) are frequent, chronic heterogeneous disorders with complex etiopathology. This review specifically focuses on the immunogenetic variants associated with bipolar disorder, recurrent depression, schizophrenia, autism spectrum disorder, and attention-deficit/hyperactivity disorder. The cumulative evidence suggests that abnormal immune processes may play a pivotal role in inducing...

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Adaptive Immunity
PGC gene
Genetic Predisposition to Disease
Immunity, Innate
Immunogenetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mental Disorders

Neurodevelopmental Disorders

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PMID: 41921887
DOI: 10.1016/j.biopsych.2026.03.996

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PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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