Article
Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure.
Schizophrenia bulletin - 1 Nov 2012
Bamne Mikhil, Wood Joel, Chowdari Kodavali, Watson Annie M, Celik Cemil, Mansour Hader, Klei Lambertus, Gur Ruben C, Bradford L DiAnne, Calkins Monica E, Santos Alberto B, Edwards Neil, Kwentus Joseph, McEvoy Joseph P, Allen Trina B, Savage Robert M, Nasrallah Henry A, Gur Raquel E, Perry Rodney T, Go Rodney C P, Devlin Bernie, Yolken Robert, Nimgaonkar Vishwajit L
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) implicate single nucleotide polymorphisms (SNPs) on chromosome 6p21.3-22.1, the human leukocyte antigen (HLA) region, as common risk factors for schizophrenia (SZ). Other studies implicate viral and protozoan exposure. Our study tests chromosome 6p SNPs for effects on SZ risk with and without exposure. METHOD: GWAS-significant SNPs and ancestry-informative marker...
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