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Article

TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity.

Frontiers in immunology - 1 Jan 2018

Louis Cynthia, Burns Chris, Wicks Ian

Abstract excerpt

The pathogenesis of autoimmune diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) is driven by genetic predisposition and environmental triggers that lead to dysregulated immune responses. These include the generation of pathogenic autoantibodies and aberrant production of inflammatory cytokines. Current therapies for RA and other autoimmune diseases reduce inflammation by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29559975
DOI: 10.3389/fimmu.2018.00434
PMCID: PMC5845716

Genes

TBK1
TANK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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