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Article

The AKT Axis as a Therapeutic Target in Autoimmune Diseases

30 May 2009

Abstract excerpt

Autoimmunity affects a substantial fraction of our population. In patients with autoimmune disease, the immune system recognizes self-tissues as foreign. Common autoimmune diseases include rheumatoid arthritis, diabetes mellitus, lupus and multiple sclerosis. Though different target organs may be affected in different autoimmune diseases, aberrations in adaptive or innate immunity underlie all of these diseases....

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PMID: 19519464
DOI: 10.2174/187153009788452417

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