Article
Dimeric sorting code for concentrative cargo selection by the COPII coat.
Proceedings of the National Academy of Sciences of the United States of America - 3 Apr 2018
Nie Chao, Wang Huimin, Wang Rui, Ginsburg David, Chen Xiao-Wei
Abstract excerpt
The flow of cargo vesicles along the secretory pathway requires concerted action among various regulators. The COPII complex, assembled by the activated SAR1 GTPases on the surface of the endoplasmic reticulum, orchestrates protein interactions to package cargos and generate transport vesicles en route to the Golgi. The dynamic nature of COPII, however, hinders analysis with conventional biochemical assays. Here...
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