COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI.

doi:10.1083/jcb.135.4.895

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Article

COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI.

The Journal of cell biology - 1 Nov 1996

Rowe T, Aridor M, McCaffery J M, Plutner H, Nuoffer C, Balch W E

Abstract excerpt

ER to Golgi transport requires the function of two distinct vesicle coat complexes, termed COPI (coatomer) and COPII, whose assembly is regulated by the small GTPases ADP-ribosylation factor 1 (ARF1) and Sar1, respectively. To address their individual roles in transport, we have developed a new assay using mammalian microsomes that reconstitute the formation of ER-derived vesicular carriers. Vesicles released...

Topics

ADP-Ribosylation Factor 1
ADP-Ribosylation Factors
Animals
Biological Transport
Carrier Proteins
Cells, Cultured
Coated Vesicles
Coatomer Protein
Endoplasmic Reticulum
GTP-Binding Proteins
Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Golgi Apparatus

Guanosine Diphosphate

Immunomagnetic Separation

Kidney

Mammals

Membrane Proteins

Microscopy, Electron

Source

Open in PubMed Open full text

Identifiers

PMID: 8922375
DOI: 10.1083/jcb.135.4.895
PMCID: PMC2133376

Genes

ARF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8922375-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI.PMID 8922375Read ↗

Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport.Semantic proximity Read ↗

Traffic COPs of the Early Secretory PathwaySemantic proximity Read ↗

Assembly, organization, and function of the COPII coatSemantic proximity Read ↗

The role of ARF1 and rab GTPases in polarization of the Golgi stack.Semantic proximity Read ↗

Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomer.Semantic proximity Read ↗

Dimeric sorting code for concentrative cargo selection by the COPII coat.Semantic proximity Read ↗

COPI vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo.Semantic proximity Read ↗

ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation.Semantic proximity Read ↗

HPV is a cargo for the COPI sorting complex during virus entrySemantic proximity Read ↗

Rab1 and Ca2+ are required for the fusion of carrier vesicles mediating endoplasmic reticulum to Golgi transport.Semantic proximity Read ↗

Differential effects of a GTP-restricted mutant of Sar1p on segregation of cargo during export from the endoplasmic reticulum.Semantic proximity Read ↗

COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP.Semantic proximity Read ↗

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