Article
COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP.
The EMBO journal - 1 Aug 2000
Eugster A, Frigerio G, Dale M, Duden R
Abstract excerpt
We performed a systematic mapping of interaction domains on COP I subunits to gain novel insights into the architecture of coatomer. Using the two-hybrid system, we characterize the domain structure of the alpha-, beta'-, epsilon-COP and beta-, gamma-, delta-, zeta-COP coatomer subcomplexes and identify links between them that contribute to coatomer integrity. Our results demonstrate that the domain organization...
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