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Article

AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells.

Proceedings of the National Academy of Sciences of the United States of America - 30 Jan 2007

Gravotta Diego, Deora Ami, Perret Emilie, Oyanadel Claudia, Soza Andrea, Schreiner Ryan, Gonzalez Alfonso, Rodriguez-Boulan Enrique

Abstract excerpt

The epithelial-specific adaptor AP1B sorts basolateral proteins, but the trafficking routes where it performs its sorting role remain controversial. Here, we used an RNAi approach to knock down the medium subunit of AP1B (mu1B) in the prototype epithelial cell line Madin-Darby canine kidney (MDCK). Mu1B-knocked down MDCK cells displayed loss of polarity of several endogenous and exogenous basolateral markers...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17244703
DOI: 10.1073/pnas.0610700104
PMCID: PMC1785260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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