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Article

Sensitization of TRPV1 receptors by TNF‑α orchestrates the development of vincristine‑induced pain

7 Feb 2018

Abstract excerpt

Vincristine is one of the most common anticancer drugs clinically employed in the treatment of various malignancies. A major side effect associated with vincristine is the development of neuropathic pain, which is not readily relieved by available analgesics. Although efforts have been made to identify the pathogenesis of vincristine‑induced neuropathic pain, the mechanisms underlying its pathogenesis have not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29552137
DOI: 10.3892/ol.2018.7986

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