Article

Paclitaxel- and vincristine-induced neurotoxicity and drug transport in sensory neurons

2023-02-07

Abstract excerpt

Chemotherapy-induced peripheral neuropathy (CIPN) constitutes a significant health problem due to the increasing prevalence and the lack of therapies for treatment and prevention. Patients with CIPN primarily present with sensory symptoms, such as sensory disturbances that may progress to neuropathic pain in hands and feet. While pivotal for routine cancer treatment, paclitaxel and vincristine frequently cause CIP...

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Literature Corpus work: 5ad955c8-d84d-5ad9-9ccc-747a92482743
DOI: 10.1101/2023.02.07.527432

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