Article
The Polymorphism rs3024505 (C/T) Downstream of the IL10 Gene Is Associated with Crohn's Disease in Serbian Patients with Inflammatory Bowel Disease.
The Tohoku journal of experimental medicine - 1 Sept 2016
Mijac Dragana, Petrovic Irena Vukovic, Djuranovic Srdjan, Perovic Vladimir, Bojic Daniela, Culafic Djordje, Popovic Dragan, Krstic Miodrag, Jankovic Goran, Djoric Milica, Pravica Vera, Markovic Milos
Abstract excerpt
Inflammatory bowel disease (IBD), manifesting as Crohn's disease (CD) and ulcerative colitis (UC), is characterized by recurring episodes of inflammation in gastrointestinal tract, in which aberrant production of regulatory cytokine interleukin-10 (IL-10) presumably plays important role. Single nucleotide polymorphisms (SNPs) that affect IL-10 production, such as rs1800896 (G/A) at position -1082 and rs1800871...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Case-Control Studies
