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Article

Combinatorial Control of Recruitment of a Variant PRC1.6 Complex in Embryonic Stem Cells.

Cell reports - 13 Mar 2018

Huang Yikai, Zhao Wukui, Wang Congcong, Zhu Yaru, Liu Mengjie, Tong Huan, Xia Yin, Jiang Qing, Qin Jinzhong

Abstract excerpt

Though genetic data suggest that Polycomb group proteins (PcGs) are central chromatin modifiers and repressors that have been implicated in control of embryonic stem cell (ESC) pluripotency, the precise mechanism of PcG complex recruitment remains elusive, especially in mammals. We now report that the first and second MBT repeats of L3mbtl2 are important structural and functional features that are necessary and...

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Identifiers

PMID: 29539429
DOI: 10.1016/j.celrep.2018.02.072

Genes

PRC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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