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Article

Successful use of whole genome amplified DNA from multiple source types for high-density Illumina SNP microarrays.

BMC genomics - 6 Mar 2018

Dagnall Casey L, Morton Lindsay M, Hicks Belynda D, Li Shengchao, Zhou Weiyin, Karlins Eric, Teshome Kedest, Chowdhury Salma, Lashley Kerrie S, Sampson Joshua N, Robison Leslie L, Armstrong Gregory T, Bhatia Smita, Radloff Gretchen A, Davies Stella M, Tucker Margaret A, Yeager Meredith, Chanock Stephen J

Abstract excerpt

BACKGROUND: The recommended genomic DNA input requirements for whole genome single nucleotide polymorphism microarrays can limit the scope of molecular epidemiological studies. We performed a large-scale evaluation of whole genome amplified DNA as input into high-density, whole-genome Illumina® Infinium® SNP microarray. RESULTS: Overall, 6622 DNA samples from 5970 individuals were obtained from three distinct...

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PMID: 29510662
DOI: 10.1186/s12864-018-4572-6
PMCID: PMC5838969

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