Article
Performance of whole-genome amplified DNA isolated from serum and plasma on high-density single nucleotide polymorphism arrays.
The Journal of molecular diagnostics : JMD - 1 May 2008
Croft Daniel T, Jordan Rick M, Patney Heather L, Shriver Craig D, Vernalis Marina N, Orchard Trevor J, Ellsworth Darrell L
Abstract excerpt
Defining genetic variation associated with complex human diseases requires standards based on high-quality DNA from well-characterized patients. With the development of robust technologies for whole-genome amplification, sample repositories such as serum banks now represent a potentially valuable source of DNA for both genomic studies and clinical diagnostics. We assessed the performance of whole-genome amplified...
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