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Article

Effects of DNA mass on multiple displacement whole genome amplification and genotyping performance.

BMC biotechnology - 16 Sept 2005

Bergen Andrew W, Qi Ying, Haque Kashif A, Welch Robert A, Chanock Stephen J

Abstract excerpt

BACKGROUND: Whole genome amplification (WGA) promises to eliminate practical molecular genetic analysis limitations associated with genomic DNA (gDNA) quantity. We evaluated the performance of multiple displacement amplification (MDA) WGA using gDNA extracted from lymphoblastoid cell lines (N = 27) with a range of starting gDNA input of 1-200 ng into the WGA reaction. Yield and composition analysis of whole...

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Identifiers

PMID: 16168060
DOI: 10.1186/1472-6750-5-24
PMCID: PMC1249558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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