Article
High fidelity of whole-genome amplified DNA on high-density single nucleotide polymorphism arrays.
Genomics - 1 Dec 2008
Xing Jinchuan, Watkins W Scott, Zhang Yuhua, Witherspoon David J, Jorde Lynn B
Abstract excerpt
Current microarray technology allows researchers to genotype a large number of SNPs with relatively small amounts of DNA. Nevertheless, researchers and clinicians still frequently face the problem of acquiring enough high-quality DNA for analysis. Whole-genome amplification (WGA) methods offer a solution for this problem, and earlier studies have shown that WGA samples perform reasonably well in small-scale...
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