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Article

VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia.

The Journal of cell biology - 2 Apr 2018

Laban Hebatullah, Weigert Andreas, Zink Joana, Elgheznawy Amro, Schürmann Christoph, Günther Lea, Abdel Malik Randa, Bothur Sabrina, Wingert Susanne, Bremer Rolf, Rieger Michael A, Brüne Bernhard, Brandes Ralf P, Fleming Ingrid, Benz Peter M

Abstract excerpt

In ischemic vascular diseases, leukocyte recruitment and polarization are crucial for revascularization and tissue repair. We investigated the role of vasodilator-stimulated phosphoprotein (VASP) in vascular repair. After hindlimb ischemia induction, blood flow recovery, angiogenesis, arteriogenesis, and leukocyte infiltration into ischemic muscles in VASP-/- mice were accelerated. VASP deficiency also elevated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29507126
DOI: 10.1083/jcb.201702048
PMCID: PMC5881493

Genes

VASP
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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