MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.

doi:10.1161/ATVBAHA.115.306672

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Article

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2016

Schlosser Anders, Pilecki Bartosz, Hemstra Line E, Kejling Karin, Kristmannsdottir Gudlaug B, Wulf-Johansson Helle, Moeller Jesper B, Füchtbauer Ernst-Martin, Nielsen Ole, Kirketerp-Møller Katrine, Dubey Lalit K, Hansen Pernille B L, Stubbe Jane, Wrede Christoph, Hegermann Jan, Ochs Matthias, Rathkolb Birgit, Schrewe Anja, Bekeredjian Raffi, Wolf Eckhard, Gailus-Durner Valérie, Fuchs Helmut, Hrabě de Angelis Martin, Lindholt Jes S, Holmskov Uffe, Sorensen Grith L

Abstract excerpt

OBJECTIVE: Arterial injury stimulates remodeling responses that, when excessive, lead to stenosis. These responses are influenced by integrin signaling in vascular smooth muscle cells (VSMCs). Microfibrillar-associated protein 4 (MFAP4) is an integrin ligand localized to extracellular matrix fibers in the vascular wall. The role of MFAP4 in vascular biology is unknown. We aimed to test the hypothesis that MFAP4...

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Identifiers

PMID: 26564819
DOI: 10.1161/ATVBAHA.115.306672

Genes

MFAP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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