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DNA polymerase delta in dna replication and genome maintenance

13 Oct 2012

Abstract excerpt

The eukaryotic genome is in a constant state of modification and repair. Faithful transmission of the genomic information from parent to daughter cells depends upon an extensive system of surveillance, signaling, and DNA repair, as well as accurate synthesis of DNA during replication. Often, replicative synthesis occurs over regions of DNA that have not yet been repaired, presenting further challenges to genomic...

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PMID: 23065663
DOI: 10.1002/em.21745

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