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Article

A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans.

The Journal of clinical endocrinology and metabolism - 1 May 2018

McAninch Elizabeth A, Rajan Kumar B, Evans Denis A, Jo Sungro, Chaker Layal, Peeters Robin P, Bennett David A, Mash Deborah C, Bianco Antonio C

Abstract excerpt

Context: A common single nucleotide polymorphism in DIO2, Thr92AlaD2, has been associated with a transcriptome typically found in neurodegenerative diseases in postmortem human brain tissue. Objective: To determine whether Thr92AlaD2 is associated with incident Alzheimer disease (AD). Design: Population-based study; human brain tissue microarray. Setting: Community-based cohorts from Chicago and northeastern...

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Source

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Identifiers

PMID: 29481662
DOI: 10.1210/jc.2017-01196
PMCID: PMC6276710

Genes

DIO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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