Article
A comprehensive genetic association study of Alzheimer disease in African Americans.
Archives of neurology - 1 Dec 2011
Logue Mark W, Schu Matthew, Vardarajan Badri N, Buros Jacki, Green Robert C, Go Rodney C P, Griffith Patrick, Obisesan Thomas O, Shatz Rhonna, Borenstein Amy, Cupples L Adrienne, Lunetta Kathryn L, Fallin M Daniele, Baldwin Clinton T, Farrer Lindsay A
Abstract excerpt
OBJECTIVES: To evaluate the association of genetic variation with late-onset Alzheimer disease (AD) in African Americans, including genes implicated in recent genome-wide association studies of whites. DESIGN: We analyzed a genome-wide set of 2.5 million imputed markers to evaluate the genetic basis of AD in an African American population. SUBJECTS: Five hundred thirteen well-characterized African American AD...
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