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Article

Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

PloS one - 1 Jan 2012

Reitz Christiane, Tosto Giuseppe, Mayeux Richard, Luchsinger Jose A

Abstract excerpt

BACKGROUND: Recent studies showed that polymorphisms in the Fat and Obesity-Associated (FTO) gene have robust effects on obesity, obesity-related traits and endophenotypes associated with Alzheimer's disease (AD). METHODS: We used 1,877 Caucasian cases and controls from the NIA-LOAD study and 1,093 Caribbean Hispanics to further explore the association of FTO with AD. Using logistic regression, we assessed 42...

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Source

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Identifiers

PMID: 23251365
DOI: 10.1371/journal.pone.0050354
PMCID: PMC3520931

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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