Article
aBayesQR: A Bayesian Method for Reconstruction of Viral Populations Characterized by Low Diversity.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jul 2018
Ahn Soyeon, Vikalo Haris
Abstract excerpt
RNA viruses replicate with high mutation rates, creating closely related viral populations. The heterogeneous virus populations, referred to as viral quasispecies, rapidly adapt to environmental changes thus adversely affecting efficiency of antiviral drugs and vaccines. Therefore, studying the underlying genetic heterogeneity of viral populations plays a significant role in the development of effective...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
