Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recent advances in inferring viral diversity from high-throughput sequencing data.

Virus research - 15 Jul 2017

Posada-Cespedes Susana, Seifert David, Beerenwinkel Niko

Abstract excerpt

Rapidly evolving RNA viruses prevail within a host as a collection of closely related variants, referred to as viral quasispecies. Advances in high-throughput sequencing (HTS) technologies have facilitated the assessment of the genetic diversity of such virus populations at an unprecedented level of detail. However, analysis of HTS data from virus populations is challenging due to short, error-prone reads. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics
Share to Computational Biology
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to High-Throughput Nucleotide Sequencing

Share to RNA Viruses

Share to Software

Share to Viruses

Source

Identifiers

PMID: 27693290
DOI: 10.1016/j.virusres.2016.09.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recent advances in inferring viral diversity from high-throughput sequencing data.PMID 27693290Read ↗

Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations.Semantic proximity Read ↗

Evaluation of haplotype callers for next-generation sequencing of viruses.Semantic proximity Read ↗

Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing dataSemantic proximity Read ↗

Ultra-deep sequencing for the analysis of viral populations.Semantic proximity Read ↗

Algorithms for Short-Read Viral Haplotype Reconstruction: Challenges, Solutions, and Perspectives.Semantic proximity Read ↗

Strainline: full-length de novo viral haplotype reconstruction from noisy long readsSemantic proximity Read ↗

Epidemiological data analysis of viral quasispecies in the next-generation sequencing eraSemantic proximity Read ↗

aBayesQR: A Bayesian Method for Reconstruction of Viral Populations Characterized by Low Diversity.Semantic proximity Read ↗

Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reductionSemantic proximity Read ↗

Benchmarking of viral haplotype reconstruction programmes: an overview of the capacities and limitations of currently available programmes.Semantic proximity Read ↗

De novo haplotype reconstruction in viral quasispecies using paired-end read guided path findingSemantic proximity Read ↗

Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.