Article
Cross-Tissue Exploration of Genetic and Epigenetic Effects on Brain Gray Matter in Schizophrenia.
Schizophrenia bulletin - 15 Feb 2018
Lin Dongdong, Chen Jiayu, Ehrlich Stefan, Bustillo Juan R, Perrone-Bizzozero Nora, Walton Esther, Clark Vincent P, Wang Yu-Ping, Sui Jing, Du Yuhui, Ho Beng C, Schulz Charles S, Calhoun Vince D, Liu Jingyu
Abstract excerpt
Closely linking genetics and environment factors, epigenetics has been of increasing interest in psychiatric disease studies. In this work, we integrated single nucleotide polymorphisms (SNPs), DNA methylation of blood and saliva, and brain gray matter (GM) measures to explore the role of genetic...
Topics
- Adult
- Blood
- DNA Methylation
- Epigenesis, Genetic
- Female
- Gray Matter
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Saliva
- Schizophrenia
- Young Adult