Article
Using Genotype Abundance to Improve Phylogenetic Inference.
Molecular biology and evolution - 1 May 2018
DeWitt William S, Mesin Luka, Victora Gabriel D, Minin Vladimir N, Matsen Frederick A
Abstract excerpt
Modern biological techniques enable very dense genetic sampling of unfolding evolutionary histories, and thus frequently sample some genotypes multiple times. This motivates strategies to incorporate genotype abundance information in phylogenetic inference. In this article, we synthesize a stochastic process model with standard sequence-based phylogenetic optimality, and show that tree estimation is substantially...
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