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Article

Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability.

G3 (Bethesda, Md.) - 28 Mar 2018

Rossi Fabrizio, Attolini Camille Stephan-Otto, Mosquera Jose Luis, Gonzalez Cayetano

Abstract excerpt

Single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) are found at different rates in human cancer. To determine if these genetic lesions appear in Drosophila tumors we have sequenced the genomes of 17 malignant neoplasms caused by mutations in l(3)mbt, brat, aurA, or lgl We have found CNVs and SNPs in all the tumors. Tumor-linked CNVs range between 11 and 80 per sample, affecting between 92 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29467187
DOI: 10.1534/g3.117.300489
PMCID: PMC5873911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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