A deterministic analysis of genome integrity during neoplastic growth in Drosophila.

Abstract excerpt

The development of cancer has been associated with the gradual acquisition of genetic alterations leading to a progressive increase in malignancy. In various cancer types this process is enabled and accelerated by genome instability. While genome sequencing-based analysis of tumor genomes becomes increasingly a standard procedure in human cancer research, the potential necessity of genome instability for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Drosophila melanogaster
• Share to Epithelium