Article
LINT, a novel dL(3)mbt-containing complex, represses malignant brain tumour signature genes.
PLoS genetics - 1 Jan 2012
Meier Karin, Mathieu Eve-Lyne, Finkernagel Florian, Reuter L Maximilian, Scharfe Maren, Doehlemann Gunther, Jarek Michael, Brehm Alexander
Abstract excerpt
Mutations in the l(3)mbt tumour suppressor result in overproliferation of Drosophila larval brains. Recently, the derepression of different gene classes in l(3)mbt mutants was shown to be causal for transformation. However, the molecular mechanisms of dL(3)mbt-mediated gene repression are not und...
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