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Article

miRNAs Copy Number Variations Repertoire as Hallmark Indicator of Cancer Species Predisposition.

Genes - 10 Jun 2022

Vischioni Chiara, Bove Fabio, De Chiara Matteo, Mandreoli Federica, Martoglia Riccardo, Pisi Valentino, Liti Gianni, Taccioli Cristian

Abstract excerpt

Aging is one of the hallmarks of multiple human diseases, including cancer. We hypothesized that variations in the number of copies (CNVs) of specific genes may protect some long-living organisms theoretically more susceptible to tumorigenesis from the onset of cancer. Based on the statistical comparison of gene copy numbers within the genomes of both cancer-prone and -resistant species, we identified novel gene...

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Identifiers

PMID: 35741808
DOI: 10.3390/genes13061046
PMCID: PMC9223155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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