Article

<i>Drosophila</i> models of pathogenic copy-number variant genes show global and non-neuronal defects during development

2019-11-26

Abstract excerpt

<h4>ABSTRACT</h4> While rare pathogenic copy-number variants (CNVs) are associated with both neuronal and non-neuronal phenotypes, functional studies evaluating these regions have focused on the molecular basis of neuronal defects. We report a systematic functional analysis of non-neuronal defects for homologs of 59 genes within ten pathogenic CNVs and 20 neurodevelopmental genes in Drosophila melanogaster . Usi...

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Literature Corpus work: 2616add7-3dd8-5abe-b9a6-ac44a114f67d
DOI: 10.1101/855338

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