Article
Transcriptional signature of an adult brain tumor in Drosophila.
BMC genomics - 16 Apr 2004
Loop Thomas, Leemans Ronny, Stiefel Urs, Hermida Leandro, Egger Boris, Xie Fukang, Primig Michael, Certa Ulrich, Fischbach Karl-Friedrich, Reichert Heinrich, Hirth Frank
Abstract excerpt
BACKGROUND: Mutations and gene expression alterations in brain tumors have been extensively investigated, however the causes of brain tumorigenesis are largely unknown. Animal models are necessary to correlate altered transcriptional activity and tumor phenotype and to better understand how these alterations cause malignant growth. In order to gain insights into the in vivo transcriptional activity associated...
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