Article
TERT promoter mutations and prognosis in solitary fibrous tumor.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2016
Bahrami Armita, Lee Seungjae, Schaefer Inga-Marie, Boland Jennifer M, Patton Kurt T, Pounds Stanley, Fletcher Christopher D
Abstract excerpt
Solitary fibrous tumor is a mesenchymal neoplasm exhibiting a broad spectrum of biological behavior and harboring the NAB2-STAT6 fusion. Clinicopathologic parameters are currently used in risk-prediction models for solitary fibrous tumor, but the molecular determinants of malignancy in solitary fibrous tumors remain unknown. We proposed that the activation of telomere maintenance pathways confers a perpetual...
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