Article
Heat Shock Protein Reports on Proteome Stress.
Biotechnology journal - 1 Apr 2018
Liu Yu, Zhang Xin
Abstract excerpt
Proper regulation of protein homeostasis (proteostasis) is essential to maintain cellular fitness. Proteome stress causes imbalance of the proteostasis, leading to various diseases represented by neurodegenerative diseases, cancers, and metabolic disorders. The biosensor community recently embarked on the development of proteome stress sensors to report on the integrity of proteostasis in live cells. While most...
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