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Article

The stress of protein misfolding: from single cells to multicellular organisms.

Cold Spring Harbor perspectives in biology - 1 Jun 2011

Gidalevitz Tali, Prahlad Veena, Morimoto Richard I

Abstract excerpt

Organisms survive changes in the environment by altering their rates of metabolism, growth, and reproduction. At the same time, the system must ensure the stability and functionality of its macromolecules. Fluctuations in the environment are sensed by highly conserved stress responses and homeostatic mechanisms, and of these, the heat shock response (HSR) represents an essential response to acute and chronic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21536706
DOI: 10.1101/cshperspect.a009704
PMCID: PMC3098679

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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