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Article

Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2018

Wen Juyi, Liu Hongliang, Wang Lili, Wang Xiaomeng, Gu Ning, Liu Zhensheng, Xu Ting, Gomez Daniel R, Komaki Ritsuko, Liao Zhongxing, Wei Qingyi

Abstract excerpt

INTRODUCTION: Autophagy not only plays an important role in the progression of cancer but is also involved in tissue inflammatory response. However, few published studies have investigated associations between functional genetic variants of autophagy-related genes and radiation pneumonitis (RP) as well as clinical outcomes in patients with NSCLC after definitive radiotherapy. METHODS: We genotyped nine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29454863
DOI: 10.1016/j.jtho.2018.01.028
PMCID: PMC6124306

Genes

ATG10
ATG12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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