Article
Potentially functional variants of autophagy-related genes are associated with the efficacy and toxicity of radiotherapy in patients with nasopharyngeal carcinoma.
Molecular genetics & genomic medicine - 1 Dec 2019
Yang Zhiguang, Liu Zhaoyu
Abstract excerpt
BACKGROUND: Nasopharyngeal carcinoma (NPC) is one of the major invasive malignant neoplasms of head and neck, while radiotherapy is the primary therapy for NPC. Genetic variants could affect the efficacy and toxicities of radiotherapy in NPC patients. METHODS: In the current study, we aimed to investigate 10 potentially functional SNPs of autophagy-related genes (ATG) with the efficacy and toxicity of...
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