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Article

ATM polymorphisms predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy.

International journal of radiation oncology, biology, physics - 15 Mar 2013

Xiong Huihua, Liao Zhongxing, Liu Zhensheng, Xu Ting, Wang Qiming, Liu Hongliang, Komaki Ritsuko, Gomez Daniel, Wang Li-E, Wei Qingyi

Abstract excerpt

PURPOSE: The ataxia telangiectasia mutated (ATM) gene mediates detection and repair of DNA damage. We investigated associations between ATM polymorphisms and severe radiation-induced pneumonitis (RP). METHODS AND MATERIALS: We genotyped 3 potentially functional single nucleotide polymorphisms (SNPs) of ATM (rs1801516 [D1853N/5557G>A], rs189037 [-111G>A] and rs228590) in 362 patients with non-small cell lung...

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Source

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Identifiers

PMID: 23154078
DOI: 10.1016/j.ijrobp.2012.09.024
PMCID: PMC3594431

Genes

ATM

Variants

rs1801516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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