Article
A Functional Variant rs2122031 in ATG7 Is Associated with the Risk of Radiation Pneumonitis.
American journal of respiratory cell and molecular biology - 1 Aug 2025
Liu Bo, Yu Yulong, Qin Wan, Yang Li, Yi Minxiao, Xiao Lingyan, Huang Yongbiao, Zhou Xiao, Yu Shiying, Wang Yihua, Wang Cong-Yi, Tang Yang, Yuan Xianglin
Abstract excerpt
Radiation pneumonitis (RP) is characterized by inflammation and is associated with autophagy. However, the relationship between functional genetic variants of autophagy-related genes and RP remains unknown. In this study, we aimed to investigate whether genetic variants of genes involved in autophagy are associated with RP. Genotyping was conducted on a total of 301 patients for 13 SNPs of 5 genes in the...
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