Article
The host control of a clinical isolate strain of P. aeruginosa infection is independent of Nod-1 but depends on MyD88.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 May 2018
Sônego Fabiane, Castanheira Fernanda V S, Horta Catarina V, Kanashiro Alexandre, Czaikoski Paula G, Zamboni Dario S, Alves-Filho José Carlos, Cunha Fernando Q
Abstract excerpt
OBJECTIVE AND DESIGN: The objective of this study was to investigate the role of Nod1 in the recruitment of neutrophils into the infection site and in the establishment of the inflammatory response elicited by a clinical isolate strain of P. aeruginosa in vivo, while comparing it to the well-established role of MyD88 in this process. SUBJECTS: Wild-type, Nod1-/- and MyD88-/- mice, all with a C57Bl/6 background....
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