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Article

Increased Susceptibility to Pulmonary Pseudomonas Infection in Splunc1 Knockout Mice

19 Sept 2013

Abstract excerpt

The airway epithelium is the first line of host defense against pathogens. The short palate, lung, and nasal epithelium clone (SPLUNC)1 protein is secreted in respiratory tracts and is a member of the bacterial/permeability increasing (BPI) fold-containing protein family, which shares structural similarities with BPI-like proteins. On the basis of its homology with BPIs and restricted expression of SPLUNC1 in...

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PMID: 24048904
DOI: 10.4049/jimmunol.1202340

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Increased Susceptibility to Pulmonary Pseudomonas Infection in Splunc1 Knockout MicePMID 24048904Read ↗

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