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Article

Aberrant inflammatory response to Streptococcus pyogenes in mice lacking myeloid differentiation factor 88.

The American journal of pathology - 1 Feb 2010

Loof Torsten G, Goldmann Oliver, Gessner André, Herwald Heiko, Medina Eva

Abstract excerpt

Several in vitro studies have emphasized the importance of toll-like receptor/myeloid differentiation factor 88 (MyD88) signaling in the inflammatory response to Streptococcus pyogenes. Since the extent of inflammation has been implicated in the severity of streptococcal diseases, we have examined here the role of toll-like receptor/MyD88 signaling in the pathophysiology of experimental S. pyogenes infection. To...

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Source

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Identifiers

PMID: 20019195
DOI: 10.2353/ajpath.2010.090422
PMCID: PMC2808082

Genes

CXCL10
CXCL9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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