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Article

Nod1 Participates in the Innate Immune Response to Pseudomonas aeruginosa

3 Sept 2005

Abstract excerpt

The mammalian innate immune system recognizes pathogen-associated molecular patterns through pathogen recognition receptors. Nod1 has been described recently as a cytosolic receptor that detects specifically diaminopimelate-containing muropeptides from Gram-negative bacteria peptidoglycan. In the present study we investigated the potential role of Nod1 in the innate immune response against the opportunistic...

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PMID: 16150702
DOI: 10.1074/jbc.m501649200

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