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Article

Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection.

Journal of leukocyte biology - 1 Aug 2007

Charmoy Mélanie, Megnekou Rosette, Allenbach Cindy, Zweifel Christine, Perez Cynthia, Monnat Katia, Breton Mélanie, Ronet Catherine, Launois Pascal, Tacchini-Cottier Fabienne

Abstract excerpt

Polymorphonuclear neutrophils (PMN) are key components of the inflammatory response contributing to the development of pathogen-specific immune responses. Following infection with Leishmania major, neutrophils are recruited within hours to the site of parasite inoculation. C57BL/6 mice are resistant to infection, and BALB/c mice are susceptible to infection, developing unhealing, inflammatory lesions. In this...

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Identifiers

PMID: 17449725
DOI: 10.1189/jlb.0706440

Genes

TLR2
TLR7
TLR9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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