Article
Impact of the Polymorphism rs9264942 near the HLA-C Gene on HIV-1 DNA Reservoirs in Asymptomatic Chronically Infected Patients Initiating Antiviral Therapy.
Journal of immunology research - 1 Jan 2017
Herráiz-Nicuesa Laura, Hernández-Flórez Diana Carolina, Valor Lara, García-Consuegra Sonia, Navarro-Valdivieso Juan Paulo, Fernández-Cruz Eduardo, Rodríguez-Sainz Carmen
Abstract excerpt
Several genome-wide association studies have identified a polymorphism located 35 kb upstream of the coding region of HLA-C gene (rs9264942; termed -35 C/T) as a host factor significantly associated with the control of HIV-1 viremia in untreated patients. The potential association of this host genetic polymorphism with the viral reservoirs has never been investigated, nor the association with the viral control in...
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